Symbol
Name
ID

Tfap2a
transcription factor AP-2, alpha
MGI:104671

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Facial palsy	Agenesis of cerebellar vermis	Intellectual disability, mild	Seizure
Disease(s) Associated with TFAP2A
branchiooculofacial syndrome

Mouse Phenotypes

nervous system phenotype

abnormal neural tube closure

incomplete rostral neuropore closure

open neural tube

decreased cochlear nerve compound action potential

abnormal forebrain morphology

anencephaly

exencephaly

abnormal cranial ganglia morphology

abnormal cochlear ganglion morphology

abnormal glossopharyngeal ganglion morphology

small trigeminal ganglion

abnormal vagus ganglion morphology

abnormal vestibular ganglion morphology

abnormal cranial nerve morphology

abnormal facial nerve morphology

absent oculomotor nerve

Availability

Mouse Genotype

Tfap2a^tm1.1Hsv/Tfap2a^tm1.1Hsv

Tfap2a^tm1Hsv/Tfap2a^tm1Hsv

Tfap2a^tm1Jae/Tfap2a^tm1Jae

Tfap2a^tm1Will/Tfap2a^tm1Will

Tfap2a^Mhdador/Tfap2a⁺

Tfap2a^tm1Jae/Tfap2a⁺

Tfap2a^tm1Will/Tfap2a^tm2.1Will

Tfap2a^tm1Hsv/Tfap2a^tm2Will
H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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